Band of Bugs sports a cel-shaded look that gives the game a bright, beautiful appearance. Characters have their own small traits, like a praying mantis with prosthetic limb made of sticks, which give them a small bit of personality. The grid-based maps are presented from an isometric point of view and are every bit as colorful as the characters - perhaps too colorful. The viewpoint and bright colors can create situations where it is hard to tell where units are on the map. It never gets so bad that it cripples the gameplay, and most can be picked out if you look for them, though it does hamper the ability to quickly make decisions based on unit positions.
Audio is pretty good, though it is limited mostly to background music that is oddly reminiscent of what you would expect to hear during an episode of Pee-Wee's Playhouse. Characters "speak" during mission briefings, though in a warbly bug speak. This is usually an easy way to annoy players, though the tones are downplayed enough that they sound kind of cool.